Chemical Structure : Ronacaleret
CAS No.:
753449-67-1
Ronacaleret
(SB-751689;SB751689)
Catalog No. : PC-61505Not For Human Use, Lab Use Only.
Ronacaleret (SB751689) is a potent calcium sensing receptor (CaSR) negative allosteric modulator with IC50 of 146 nM for hCaSR.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6150501
Biological Activity
Ronacaleret (SB751689) is a potent calcium sensing receptor (CaSR ) negative allosteric modulator with IC50 of 146 nM for hCaSR.
Physicochemical Properties
M.Wt
447.523
Formula
C25H31F2NO4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
3-[3-[(2R)-3-[[1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl]amino]-2-hydroxypropoxy]-4,5-difluorophenyl]propanoic acid
References
1. Balan G, et al. Bioorg Med Chem Lett.
2. Fitzpatrick LA, et al. J Clin Endocrinol Metab.
3. Fitzpatrick LA, et al. Bone.
4. Caltabiano S, et al. Bone.
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