Rosolutamide (ASC-JM17, ALZ-003) | Nrf1/Nrf2 activator

Chemical Structure : Rosolutamide

Rosolutamide (ASC-JM17, ALZ-003, ALZ003)

Catalog No.: PC-25023Not For Human Use, Lab Use Only.

Rosolutamide (ASC-JM17) is a curcumin analog, an orally active, potent Nrf1 and Nrf2 activator, activates Nrf1, Nrf2, and heat shock factor 1 (Hsf1), which in turn activates the expression of proteasome subunits, antioxidant enzymes, and molecular chaperones.

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Biological Activity

Rosolutamide (ASC-JM17, ALZ-003) is a curcumin analog, an orally active, potent Nrf1 and Nrf2 activator, activates Nrf1, Nrf2, and heat shock factor 1 (Hsf1), which in turn activates the expression of proteasome subunits, antioxidant enzymes, and molecular chaperones.

Physicochemical Properties

M.Wt	464.56
Formula	C28H32O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES

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Rosolutamide (ASC-JM17, ALZ-003, ALZ003)

Biological Activity

Physicochemical Properties

References

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