Rovadicitinib (TQ05105) | JAK/ROCK inhibitor

Chemical Structure : Rovadicitinib

Rovadicitinib (TQ05105, TQ-05105)

Catalog No.: PC-25191Not For Human Use, Lab Use Only.

Rovadicitinib (TQ05105) is a potent, oral dual JAK1/2 and ROCK1/2 inhibitor targeting inflammatory and fibrotic components of chronic graft-versus-host disease (cGVHD).

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Biological Activity

Rovadicitinib (TQ05105) is a potent, oral dual JAK1/2 and ROCK1/2 inhibitor targeting inflammatory and fibrotic components of chronic graft-versus-host disease (cGVHD).

Physicochemical Properties

M.Wt	321.39
Formula	C17H19N7
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-3-(3-amino-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile

References

1. Zhao YM, et al. Blood. 2025 Jun 12;145(24):2857-2872.

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Rovadicitinib (TQ05105, TQ-05105)

Biological Activity

Physicochemical Properties

References

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