S-309309 | MGAT2 inhibitor | Probechem Biochemicals

Chemical Structure : S-309309

Catalog No.: PC-23933Not For Human Use, Lab Use Only.

S-309309 is a potent, selective and orally bioavailable monoacylglycerol acyltransferase 2 (MGAT2) inhibitor with potential treatment for obesity.

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Biological Activity

S-309309 is a potent, selective and orally bioavailable monoacylglycerol acyltransferase 2 (MGAT2) inhibitor with potential treatment for obesity.

M.Wt	517.51
Formula	C23H21F2N5O5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[(4R)-5,7-Difluoro-2'-(5-methylpyridin-2-yl)-4'-oxo-2,2',3,4',5',7'-hexahydrospiro[1-benzopyran-4,6'-pyrazolo[4,3-c]pyridin]-3'-yl]-2-(methanesulfonyl)acetamide

1. Miyano T, et al. Pharmaceutics. 2024 Jul 17;16(7):949.

2. Patent WO 2019/013311 A1.