S18616 | TAAR1 agonist | Probechem Biochemicals

Chemical Structure : S18616

S18616 (S 18616)

Catalog No.: PC-22309Not For Human Use, Lab Use Only.

S18616 is a potent, selective trace amine-associated receptor 1 (TAAR1) agonist with EC50 of 15 nM, also displayshigh affinity at native rat alpha(2)-adrenoceptor (AR) with pKi of 9.8.

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Biological Activity

S18616 is a potent, selective trace amine-associated receptor 1 (TAAR1) agonist with EC50 of 15 nM, also displayshigh affinity at native rat alpha(2)-adrenoceptor (AR) with pKi of 9.8.

Physicochemical Properties

M.Wt	236.70
Formula	C12H13ClN2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S)-8-Chloro-3,4-dihydrospiro[naphthalene-2(1H),4′(5′H)-oxazol]-2′-amine

References

1. Grossi G, et al. Molecules. 2024 Apr 11;29(8):1739.

2. Millan MJ, et al. J Pharmacol Exp Ther. 2000 Dec;295(3):1192-205.

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S18616 (S 18616)

Biological Activity

Physicochemical Properties

References

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