| Cat. No. |
Product Name |
Information |
| PC-28375 |
Ulotaront hydrochloride
TAAR1 agonist
|
Ulotaront hydrochloride (SEP-363856, SEP-856) is a psychotropic agent and selective agonist of trace amine receptor 1 (TAAR1) and 5-HT1A receptor with EC50 of 0.14 uM and 2.3 uM for human TAAR1 and 5-HT1A receptor respectively, shows no appreciable action at dopamine D2 receptors. |
| PC-22309 |
S18616
TAAR1 agonist
|
S18616 is a potent, selective trace amine-associated receptor 1 (TAAR1) agonist with EC50 of 15 nM, also displayshigh affinity at native rat alpha(2)-adrenoceptor (AR) with pKi of 9.8. |
| PC-72628 |
Ralmitaront
TAAR1 modulator
|
Ralmitaront (RO6889450, RG7906) is a potent, orally active trace amine-associated receptor 1 (TAAR-1) modulator as a neuroleptic agent. |
| PC-72627 |
Ulotaront
TAAR1 agonist
|
Ulotaront (SEP-363856, SEP-856) is a psychotropic agent and selective agonist of trace amine receptor 1 (TAAR1) and 5-HT1A receptor with EC50 of 0.14 uM and 2.3 uM for human TAAR1 and 5-HT1A receptor respectively, shows no appreciable action at dopamine D2 receptors. |
| PC-72353 |
RTI-7470-44
TAAR1 antagonist
|
RTI-7470-44 is a potent, selective human trace amine-associated receptor subtype 1 (hTAAR1) inhibitor with IC50 of 8.4 nM in vitro cAMP functional assay. |
| PC-61077 |
RO 5203648
TAAR1 agonist
|
RO 5203648 is a potent and selective TAAR1 partial agonist with Ki of 0.5, 1.0, 6.8 and 2.6 nM for mouse, rat, human and monkey TAAR1, respectively. |
| PC-61076 |
RO 5073012
TAAR1 agonist
|
RO 5073012 is a potent, selective, orally active TAAR1 partial agonist with Ki of 6 nM, EC50 of 23 nM (hTAAR1), 140-fold selectivity over β2 adrenergic receptors. |
| PC-61075 |
RO5166017
TAAR1 agonist
|
RO5166017 is a potent, selective TAAR1 agonist with Ki of 1.9, 2.7, 31 and 24 nM for mouse, rat, cynomolgus monkey and human TAAR1 stably expressed in HEK293 cells. |
| PC-61073 |
EPPTB
TAAR1 antagonist
|
EPPTB (Ro 5212773) is a potent, selective mouse TAAR1 antagonist that potently antagonizes cAMP production induced by 1.5 uM β-phenylethylamine with IC50 of 27.5 nM, Ki of 1 nM. |
| PC-61072 |
RO5263397
TAAR1 agonist
|
RO 5263397 is a highly potent, selective and orally bioavailable trace amine-associated receptor 1 (TAAR1) partial agonist with EC50 of 17 nM, >1,000-fold selectivity over human adrenergic α2A receptor. |
| PC-61071 |
RO 5256390
TAAR1 agonist
|
RO 5256390 is a highly potent, selective and orally bioavailable trace amine-associated receptor 1 (TAAR1) full agonist with EC50 of 18 nM, >500-fold selectivity over human adrenergic α2A receptor. |
| PC-22880 |
TAAR1 agonist 65 hydrochloride
TAAR1 agonist
|
TAAR1 agonist 65 hydrochloride is potent, selective agonist of trace amine-associated receptor 1 (TAAR1) with pEC50 of 7.6, shows physiological and antipsychotic-like effects in vivo. |
