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Ulotaront

Chemical Structure : Ulotaront

CAS No.: 1310426-33-5

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Ulotaront (SEP-363856, SEP-856)

Catalog No.: PC-72627Not For Human Use, Lab Use Only.

Ulotaront (SEP-363856, SEP-856) is a novel psychotropic agent with agonism at trace amine receptor 1 (TAAR1) and 5-HT1A receptors but no appreciable action at dopamine D2 receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Ulotaront (SEP-363856, SEP-856) is a novel psychotropic agent with agonism at trace amine receptor 1 (TAAR1) and 5-HT1A receptors but no appreciable action at dopamine D2 receptors.
    Ulotaront significantly reduced the ketamine-induced increase in dopamine synthesis capacity.

    Physicochemical Properties

    M.Wt 183.269
    Formula C9H13NOS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-[(7S)-5,7-dihydro-4H-thieno[2,3-c]pyran-7-yl]-N-methylmethanamine

    References

    1. Dedic N, et al. J Pharmacol Exp Ther. 2019 Oct;371(1):1-14.

    2. Koblan KS, et al. N Engl J Med. 2020 Apr 16;382(16):1497-1506.

    3. Mol Psychiatry. 2021 Aug 10. doi: 10.1038/s41380-021-01250-7.

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