SABRAC

Chemical Structure : SABRAC

Catalog No.: PC-22606Not For Human Use, Lab Use Only.

SABRAC is a highly potent, irreversible inhibitor of acid ceramidase with Ki of 29.7 nM, induces apoptosis and provides a benefit in mice survival in IDH1 mut oligodendroglioma.

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Biological Activity

SABRAC is a highly potent, irreversible inhibitor of acid ceramidase with Ki of 29.7 nM, induces apoptosis and provides a benefit in mice survival in IDH1 mut oligodendroglioma.

Physicochemical Properties

M.Wt	422.45
Formula	C20H40BrNO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Bromo-N-[(1S,2R)-2-hydroxy-1-(hydroxymethyl)heptadecyl]acetamide

References

1. Ordóñez YF, et al. J Am Chem Soc. 2019 May 15;141(19):7736-7742.

2. Muley H, et al. bioRxiv [Preprint]. 2024 Apr 29:2024.04.27.591426.

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SABRAC

Biological Activity

Physicochemical Properties

References

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