Chemical Structure : SAL-0010042
Catalog No.: PC-23658Not For Human Use, Lab Use Only.
SAL-0010042 is a fast-acting and potent Plasmodium falciparum PDEβ inhibitor with IC50 of 10.8 nM for cGMP hydrolysis in crude gametocyte membrane preparations, and EC50 of 142 nM for 3D7 blood stage.
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SAL-0010042 is a fast-acting and potent Plasmodium falciparum PDEβ inhibitor with IC50 of 10.8 nM for cGMP hydrolysis in crude gametocyte membrane preparations, and EC50 of 142 nM for 3D7 blood stage.
M.Wt | 286.31 | |
Formula | C15H15FN4O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Gomez-Gonzalez PJ, et al. Sci Adv. 2024 Dec 6;10(49):eadq1383.
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