Chemical Structure : SAM486A
CAS No.:
149400-88-4
SAM486A
(Sardomozide, CGP 48664)
Catalog No. : PC-24844Not For Human Use, Lab Use Only.
SAM486A (Sardomozide) is a highly potent, selective S-adenosylmethionine decarboxylase (SAMDC) inhibitor with IC50 of 5 nM, inhibits intracellular spermidine and spermine pools.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2484401
Biological Activity
SAM486A (Sardomozide) is a highly potent, selective S-adenosylmethionine decarboxylase (SAMDC) inhibitor with IC50 of 5 nM, inhibits intracellular spermidine and spermine pools.
Physicochemical Properties
M.Wt
230.28
Formula
C11H14N6
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-(4-Carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazine-1-carboximidamide
References
1. Stanek J, et al. J Med Chem. 1993 Jul 23;36(15):2168-71.
2. Regenass U, et al. Cancer Res. 1994 Jun 15;54(12):3210-7.
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