Chemical Structure : SANT-1
CAS No.:
304909-07-7
SANT-1
(SANT1)
Catalog No. : PC-62171Not For Human Use, Lab Use Only.
SANT-1 is a potent, cell-permeable Smoothened inhibitor (Kd=1.2 nM) that inhibits Sonic hedgehog (Shh) signaling.
Packing Price Stock Quantity 10 mg $118 In stock 0 1 2 3 4 5 25 mg $188 In stock 0 1 2 3 4 5 50 mg $288 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6217101
Biological Activity
SANT-1 is a potent, cell-permeable Smoothened inhibitor (Kd=1.2 nM) that inhibits Sonic hedgehog (Shh) signaling.
Physicochemical Properties
M.Wt
373.504
Formula
C23H27N5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
N-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine
References
1. Chen JK, et al. Proc Natl Acad Sci U S A.
2. Cohen JR, et al. BMC Cancer.
3. Dixit D, et al. Cancer Lett.
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