SANT-2 | Hedgehog inhibitor, Smo inhibitor

Chemical Structure : SANT-2

CAS No.: 329196-48-7

SANT-2 (SANT2)

Catalog No.: PC-25923Not For Human Use, Lab Use Only.

SANT-2 is a potent Hh-signaling pathway antagonist and Smoothened receptor antagonist, inhibits Shh-dependent translocation of Smo, interferes with the expression of Gli1.

Packing	Price	Stock
10 mg	$78	In stock
25 mg	$128	In stock
50 mg	$198	In stock
100 mg		Get quote

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Biological Activity

SANT-2 is a potent Hh-signaling pathway antagonist and Smoothened receptor antagonist, inhibits Shh-dependent translocation of Smo, interferes with the expression of Gli1.

Physicochemical Properties

M.Wt	479.96
Formula	C26H26ClN3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-(1H-Benzo[d]imidazol-2-yl)-4-chlorophenyl)-3,4,5-triethoxybenzamide

References

1. Büttner A, et al. Bioorg Med Chem. 2009 Jul 15;17(14):4943-54.

2. Rominger CM, et al. J Pharmacol Exp Ther. 2009 Jun;329(3):995-1005.

3. Chen JK, et al. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14071-6.

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SANT-2 (SANT2)

Biological Activity

Physicochemical Properties

References

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