Catalog No.: PC-60622Not For Human Use, Lab Use Only.
SB332235 (SB-332235) is a potent, selective and competitive CXCR2 inhibitor that selectively inhibits CXCR2-mediated recruitment of β-arrestin-2 with pKi of 8.92.
SB332235 (SB-332235) is a potent, selective and competitive CXCR2 inhibitor that selectively inhibits CXCR2-mediated recruitment of β-arrestin-2 with pKi of 8.92.
SB332235 inhibits N-Ac-PGP- and CXCL1-induced neutrophil influx and the increased pulmonary tissue MPO levels in micelung tissue homogenates.
SB332235 effectively inhibits smoke-induced inflammatory and mucus hypersecretory changes in rat lung.
SB332235 also attenuates microglial inflammatory reactivity induced by Aβ1-42 intrahippocampal injection in animal model of Alzheimer’s disease.
