Chemical Structure : SB-334867 free base
CAS No.:
792173-99-0
SB-334867 free base
(SB334867A free base;SB334867 free base;SB 334867 free base)
Catalog No. : PC-42731Not For Human Use, Lab Use Only.
SB-334867 is the first selective Orexin-1 receptor (OX1R) antagonist with pKb of 7.4, displays 50-fold selectivity over OX2R (pKb 5.7).
Packing Price Stock Quantity 10 mg $88 In stock 0 1 2 3 4 5 25 mg $148 In stock 0 1 2 3 4 5 50 mg $248 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5 200 mg Get quote 0 1 2 3 4 5 1 g Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4273101
Biological Activity
SB-334867 is the first selective Orexin-1 receptor (OX1R) antagonist with pKb of 7.4, displays 50-fold selectivity over OX2R (pKb 5.7).
Physicochemical Properties
M.Wt
319.3174
Formula
C17H13N5O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 49 mg/mL
Chemical Name/SMILES
Urea, N-(2-methyl-6-benzoxazolyl)-N'-1,5-naphthyridin-4-yl-
References
1. Smart D, et al. Br J Pharmacol.
2. Porter RA, et al. Bioorg Med Chem Lett.
3. Rodgers RJ, et al. Eur J Neurosci.
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