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Chemical Structure : SB-408124 hydrochloride
CAS No.: 1431697-90-3
Catalog No.: PC-45972Not For Human Use, Lab Use Only.
A potent, selective OX1 receptor antagonist with Ki of 57 nM (whole cell assay), and 27 nM (cell membrane-based SPA assay).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $72 | In stock | |
| 50 mg | $224 | In stock | |
| 100 mg | $400 | In stock |
Bulk size, bulk discount!
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A potent, selective OX1 receptor antagonist with Ki of 57 nM (whole cell assay), and 27 nM (cell membrane-based SPA assay); displays 50-fold selectivity over OX2 receptor; prevents the stimulatory effect of Olanzapine on endogenous glucose production.
| M.Wt | 392.8302 | |
| Formula | C19H19ClF2N4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Urea, N-(6,8-difluoro-2-methyl-4-quinolinyl)-N'-[4-(dimethylamino)phenyl]-, hydrochloride (1:1) |
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1. Langmead CJ, et al. Br J Pharmacol. 2004 Jan;141(2):340-6.
2. Malherbe P, et al. Mol Pharmacol. 2009 Sep;76(3):618-31.
3. Girault EM, et al. Brain Res. 2013 Aug 21;1527:238-45.
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