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SB-423562

Chemical Structure : SB-423562

CAS No.: 351490-27-2

SB-423562 (SB423562)

Catalog No.: PC-26412Not For Human Use, Lab Use Only.

SB-423562 is a potent, selective and short-acting calcium-sensing receptor (CaSR) antagonist with IC50 of 73 nM (in vitro inhibition of CaSR mediated signaling in HEK-293 cells transfected with human CaSR).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SB-423562 is a potent, selective and short-acting calcium-sensing receptor (CaSR) antagonist with IC50 of 73 nM (in vitro inhibition of CaSR mediated signaling in HEK-293 cells transfected with human CaSR).

Physicochemical Properties

M.Wt 436.55
Formula C26H32N2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-3-(4-Cyano-3-(3-((1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)phenyl)propanoic acid

References

1. Sanjay Kumar, et al. Bone. 2010 Feb;46(2):534-42.

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