SB-583831 | GPR132 agonist | Probechem Biochemicals

Chemical Structure : SB-583831

SB-583831 (SB583831)

Catalog No.: PC-27048Not For Human Use, Lab Use Only.

SB-583831 is a potent, selective agonist of G‐protein‐coupled receptor GPR132 (G2A) with pEC50 of 7.7 and 7.3 in yeast and β‐arrestin assays (human GPR132a).

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Biological Activity

SB-583831 is a potent, selective agonist of G‐protein‐coupled receptor GPR132 (G2A) with pEC50 of 7.7 and 7.3 in yeast and β‐arrestin assays (human GPR132a).
SB-583831 does not activates GPR68 or CB2 in yeast expressing either GPR68 or CB2 up to 100 uM.

Physicochemical Properties

M.Wt	512.21
Formula	C23H18Cl4N2O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3',4'-dichloro-N-(2-((3,4-dichlorophenethyl)amino)-2-oxoethyl)-6-hydroxy-[1,1'-biphenyl]-3-carboxamide

References

1. James R Foster, et al. Pharmacol Res Perspect. 2019 Nov 21;7(6):e00542.

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SB-583831 (SB583831)

Biological Activity

Physicochemical Properties

References

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