SB-633825

Chemical Structure : SB-633825

CAS No.: 956613-01-7

Catalog No.: PC-25741Not For Human Use, Lab Use Only.

SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively, inhibits cancer cell growth and angiogenesis.

Packing	Price	Stock
5 mg	$188	In stock
10 mg	$298	In stock
25 mg	$498	In stock
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Biological Activity

SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively, inhibits cancer cell growth and angiogenesis.

Physicochemical Properties

M.Wt	483.59
Formula	C28H25N3O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(5-(6-Methoxynaphthalen-2-yl)-1-methyl-2-(2-methyl-4-(methylsulfonyl)phenyl)-1H-imidazol-4-yl)pyridine

References

1. Elkins JM, et al. Nat Biotechnol. 2016 Jan;34(1):95-103.

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SB-633825

Biological Activity

Physicochemical Properties

References

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