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SB1578

Chemical Structure : SB1578

CAS No.: 937273-04-6

SB1578

Catalog No.: PC-22994Not For Human Use, Lab Use Only.

SB1578 is a potent, selective JAK2/FLT3 inhibitor with IC50 of 46/60 nM respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SB1578 is a potent, selective JAK2/FLT3 inhibitor with IC50 of 46/60 nM respectively.

Physicochemical Properties

M.Wt 462.55
Formula C26H30N4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-44-(2-(pyrrolidin-1-yl)ethoxy)-6,11-dioxa-3-aza-2(4,2)-pyrimidina-1(2,5)-furana-4(1,3)-benzenacyclododecaphan-8-ene

References

1. Anthony D William, et al. J Med Chem. 2012 Mar 22;55(6):2623-40.

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