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Chemical Structure : SB 265610
CAS No.: 211096-49-0
Catalog No.: PC-60621Not For Human Use, Lab Use Only.
SB 265610 is a potent, selective, reversible CXCR2 antagonist with with Kd of 3.48 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $148 | In stock | |
| 10 mg | $228 | In stock | |
| 25 mg | $368 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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SB 265610 is a potent, selective, reversible CXCR2 antagonist with with Kd of 3.48 nM.
SB 265610 inhibits protein nitration induced by hyperoxia, reduces radical formation in hyperoxia-exposed newborn rat lung.
SB 265610 also induces G1 arrest, ans shows anti-proliferative activity in in IL8-rich tumor microenvironments.
| M.Wt | 357.16 | |
| Formula | C14H9BrN6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
100 mM in DMSO |
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| Chemical Name/SMILES |
N-(2-Bromophenyl)-N'-(7-cyano-1H-benzotriazol-4-yl)urea |
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1. de Kruijf P, et al. J Pharmacol Exp Ther. 2009 May;329(2):783-90.
2. Bradley ME, et al. Br J Pharmacol. 2009 Sep;158(1):328-38.
3. de Kruijf P, et al. Mol Pharmacol. 2011 Dec;80(6):1108-18.
4. Goda AE, et al. Anticancer Res. 2015 Jun;35(6):3235-43.
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