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SB5-171

Chemical Structure : SB5-171

CAS No.: 3088376-92-2

SB5-171

Catalog No.: PC-25995Not For Human Use, Lab Use Only.

SB5-171 is a potent, covalent PfCLK3 inhibitor with IC50 of 10 nM, shows potent antiparasitic activity (EC50=104 nM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SB5-171 is a potent, covalent PfCLK3 inhibitor with IC50 of 10 nM, shows potent antiparasitic activity (EC50=104 nM).

Physicochemical Properties

M.Wt 593.66
Formula C29H31N5O7S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(2-{2-Methoxy-5-[(4-{2-[(methylsulfamoyl)oxy]acetyl}piperazin-1-yl)methyl]phenyl}-1H-pyrrolo[2,3-b]pyridin-4-yl)benzoic acid

References

1. Brettell SB, et al. J Med Chem. 2026 Jan 31. doi: 10.1021/acs.jmedchem.5c03342.

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