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Chemical Structure : SBI-0797750
Catalog No.: PC-72936Not For Human Use, Lab Use Only.
SBI-0797750 (SBI 0797750) is a potent, fully selective PfGluPho inhibitor with robust nanomolar activity against recombinant PfGluPho, PvG6PD, and P. falciparum blood-stage parasites.
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SBI-0797750 (SBI 0797750) is a potent, fully selective PfGluPho inhibitor with robust nanomolar activity against recombinant PfGluPho, PvG6PD, and P. falciparum blood-stage parasites.
SBI-0797750 disturbs the cytosolic glutathione-dependent redox potential, as well as the cytosolic and mitochondrial H2O2 homeostasis of P. falciparum blood stages, at low nanomolar concentrations.
SBI-0797750 does not harm red blood cell (RBC) integrity and phagocytosis and thus does not promote anemia.
| M.Wt | 455.548 | |
| Formula | C24H26FN3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Isabell Berneburg, et al. Antimicrob Agents Chemother. 2022 Mar 10;e0210921.
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