SBI-2130 | SHP2 inhibitor | Probechem Biochemicals

Chemical Structure : SBI-2130

Catalog No.: PC-38183Not For Human Use, Lab Use Only.

SBI-2130 (SBI 2130) is a novel furanylbenzamide molecule inhibitor of both WT and oncogenic SHP2 with IC50 of 0.22/5.0 uM for Wt SHP2/SHP2-E76K.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SBI-2130 (SBI 2130) is a novel furanylbenzamide molecule inhibitor of both WT and oncogenic SHP2 with IC50 of 0.22/5.0 uM for Wt SHP2/SHP2-E76K.

M.Wt	454.5
Formula	C26H18N2O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-N-(4-aminophenyl)-2-hydroxy-5-(5-((3-oxobenzo[b]thiophen-2(3H)-ylidene)methyl)furan-2-yl)benzamide

1. Raveendra-Panickar D, et al. J Biol Chem. 2022 Jan;298(1):101477.