SBI-9635

Chemical Structure : SBI-9635

Catalog No.: PC-28528Not For Human Use, Lab Use Only.

SBI-9635 is a small-molecule inhibitor of the Tau-LRP1 (low-density lipoprotein receptor-related protein 1) interaction with IC50 of 11 uM in LRP1-BD4-L57 TR-FRET assay, reduces tau uptake in H4 neuroglioma cells.

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Biological Activity

Physicochemical Properties

M.Wt	344.21
Formula	C17H14BrNO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-bromo-1-(2,4-dimethylbenzyl)indoline-2,3-dione

References

1. Wang C, et al. ACS Chem Biol. 2026 Oct 13. doi: 10.1021/acschembio.6c00599.

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SBI-9635

Biological Activity

Physicochemical Properties

References

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