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Chemical Structure : SC-66
CAS No.: 871361-88-5
Catalog No.: PC-45738Not For Human Use, Lab Use Only.
SC66 is an allosteric Akt inhibitor, exhibits a dual inhibitory activity that directly interferes with the PH domain binding to PIP3 and facilitates Akt ubiquitination.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $78 | In stock | |
| 25 mg | $118 | In stock | |
| 50 mg | $188 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
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SC66 is an allosteric Akt inhibitor, exhibits a dual inhibitory activity that directly interferes with the PH domain binding to PIP3 and facilitates Akt ubiquitination.
SC66 has anticancer activity mouse xenograft tumor model.
| M.Wt | 276.3324 | |
| Formula | C18H16N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 34 mg/mL |
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| Chemical Name/SMILES |
Cyclohexanone, 2,6-bis(4-pyridinylmethylene)-, (2E,6E)- |
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1. Jo H, et al. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6486-91.
2. Cusimano A, et al. Oncotarget. 2015 Jan 30;6(3):1707-22.
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