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You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Matrix Metalloproteinase (MMP)-SC-78080
SC-78080

Chemical Structure : SC-78080

CAS No.: 226396-25-4

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SC-78080 (SD-2590, SC78080)

Catalog No.: PC-72036Not For Human Use, Lab Use Only.

SC-78080 (SD-2590) is a potent, selective inhibitor of MMP2/9/13 with IC50 of <0.1/0.18/<0.1 nM, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SC-78080 (SD-2590) is a potent, selective inhibitor of MMP2/9/13 with IC50 of <0.1/0.18/<0.1 nM, respectively.
    SC-78080 shows weaken inhibitory effect on MMP3/8, and no inhibition on MMP1/7.

    Physicochemical Properties

    M.Wt 518.504
    Formula C22H25F3N2O7S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-hydroxy-1-(2-methoxyethyl)-4-((4-(4-(trifluoromethoxy)phenoxy)phenyl)sulfonyl)piperidine-4-carboxamide

    References

    1. Daniel P Becker, et al. J Med Chem. 2010 Sep 23;53(18):6653-80.

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