Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-SC57461A
SC57461A

Chemical Structure : SC57461A

CAS No.: 423169-68-0

SC57461A (SC 57461A, SC-57461A)

Catalog No.: PC-70334Not For Human Use, Lab Use Only.

SC57461A (SC 57461A) is a potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM.

Packing Price Stock Quantity
10 mg $138 In stock
25 mg $238 In stock
50 mg $418 In stock
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SC57461A (SC 57461A) is a potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM.
SC57461A (SC 57461A) inhibits calcium ionophore-induced LTB(4) production in human whole blood (IC50=49 nM).
SC57461A (SC 57461A) has no effect on production of the cyclooxygenase metabolite thromboxane B(2).
SC57461A (SC 57461A) is orally active in vivo.

Physicochemical Properties

M.Wt 363.88
Formula C20H25NO3.HCl
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-((3-(4-benzylphenoxy)propyl)(methyl)amino)propanoic acid hydrochloride

References

1. Askonas LJ, et al. J Pharmacol Exp Ther. 2002 Feb;300(2):577-82.

2. Kachur JF, et al. J Pharmacol Exp Ther. 2002 Feb;300(2):583-7.

3. Penning TD, et al. J Med Chem. 2002 Aug 1;45(16):3482-90.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: