Chemical Structure : SCH-479833
Catalog No.: PC-20802Not For Human Use, Lab Use Only.
SCH-479833 is a potent, specific and orally active CXCR1 and CXCR2 antagonist with Ki of 0.17 and 7 nM, respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
SCH-479833 is a potent, specific and orally active CXCR1 and CXCR2 antagonist with Ki of 0.17 and 7 nM, respectively.
SCH-479833 inhibits microvessel density in human melanoma tumors, inhibits melanoma cell motility and invasion.
SCH-479833 inhibits A375SM cell proliferation and ERK1/2 signaling.
SCH-479833 (100 mg/kg, i.p.) inhibits proliferation and survival in human melanoma tumor mice model.
M.Wt | 393.44 | |
Formula | C22H23N3O4 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
1. Singh S, et al. Clin Cancer Res. 2009 Apr 1;15(7):2380-6.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright