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Chemical Structure : SCH-479833
Catalog No.: PC-20802Not For Human Use, Lab Use Only.
SCH-479833 is a potent, specific and orally active CXCR1 and CXCR2 antagonist with Ki of 0.17 and 7 nM, respectively.
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SCH-479833 is a potent, specific and orally active CXCR1 and CXCR2 antagonist with Ki of 0.17 and 7 nM, respectively.
SCH-479833 inhibits microvessel density in human melanoma tumors, inhibits melanoma cell motility and invasion.
SCH-479833 inhibits A375SM cell proliferation and ERK1/2 signaling.
SCH-479833 (100 mg/kg, i.p.) inhibits proliferation and survival in human melanoma tumor mice model.
| M.Wt | 393.44 | |
| Formula | C22H23N3O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Singh S, et al. Clin Cancer Res. 2009 Apr 1;15(7):2380-6.
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