Chemical Structure : SD-70
CAS No.: 332173-89-4
Catalog No.: PC-70332Not For Human Use, Lab Use Only.
SD-70 is a small molecule tumor translocation inhibitor that inhibits the prostate cancer cell transcriptional program, in part by inhibition of the demethylase KDM4C (IC50=30 uM).
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SD-70 is a small molecule tumor translocation inhibitor that inhibits the prostate cancer cell transcriptional program, in part by inhibition of the demethylase KDM4C (IC50=30 uM).
SD-70represses AR transcriptional program, increases H3K9me2 levels in 293T cells.
SD-70 inhibits tumor growth in CWR22Rv1 prostate cancer xenograft mice model.
M.Wt | 310.353 | |
Formula | C18H18N2O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(furan-2-yl(8-hydroxyquinolin-7-yl)methyl)isobutyramide |
1. Jin C, et al. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9235-40.
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