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SDUY212

Chemical Structure : SDUY212

CAS No.:

SDUY212 (SDUY-212)

Catalog No.: PC-28551Not For Human Use, Lab Use Only.

SDUY212 is a potent TRPM7 inhibitor with IC50 of 0.5 uM, effectively suppresses the proliferation, migration and invasion of MCF-7 and MDA-MB-231 breast cancer cells while inducing apoptosis and cell-cycle arrest.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SDUY212 is a potent TRPM7 inhibitor with IC50 of 0.5 uM, effectively suppresses the proliferation, migration and invasion of MCF-7 and MDA-MB-231 breast cancer cells while inducing apoptosis and cell-cycle arrest.

Physicochemical Properties

M.Wt 297.79
Formula C17H16ClN3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-5-chloro-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1H-benzo[d]imidazol-2-amine

References

1. Zhang N, et al. J Med Chem. 2026 Oct 8;69(19):22208-22230.

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