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SFV785

Chemical Structure : SFV785

CAS No.: 1188497-23-5

SFV785 (SFV 785, SFV-785, SRPIN-785)

Catalog No.: PC-63346Not For Human Use, Lab Use Only.

SFV785 (SRPIN-785) is a derivative of SRPIN340 that selectively inhibits NTRK1 and MAPKAPK5 kinase, shows anti-viral activity on HCV, DENV and yellow fever viruses.

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    Biological Activity

    SFV785 (SRPIN-785) is a derivative of SRPIN340 that selectively inhibits NTRK1 and MAPKAPK5 kinase, shows anti-viral activity on HCV, DENV and yellow fever viruses.
    SFV785 inhibits DENV propagation without inhibiting DENV RNA synthesis or translation.
    SFV785 inhibits the recruitment and encapsulation of the nucleocapsid in specific ER compartments during the DENV assembly process.

    Physicochemical Properties

    M.Wt 436.497
    Formula C21H23F3N4OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-[2-(azocan-1-yl)-5-(trifluoromethyl)phenyl]-3-[(pyridin-3-yl)carbonyl]thiourea

    References

    1. Anwar A, et al. PLoS One. 2011;6(8):e23246.

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