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Chemical Structure : SGC2085 hydrochloride
CAS No.: 1821908-49-9
Catalog No.: PC-38535Not For Human Use, Lab Use Only.
SGC-2085 hydrochloride is a potent, selective protein arginine methyltransferase PRMT4 (CARM1) inhibitor with IC50 of 50 nM, displays >100-fold selectivity over other PRMTs (PRMT6 IC50=5.3 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $158 | In stock | |
| 5 mg | $328 | In stock | |
| 10 mg | $528 | In stock | |
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| 100 mg | Get quote |
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SGC-2085 hydrochloride is a potent, selective protein arginine methyltransferase PRMT4 (CARM1) inhibitor with IC50 of 50 nM, displays >100-fold selectivity over other PRMTs (PRMT6 IC50=5.3 uM).
SGC-2085 also shows complete selectivity against a panel of 21 human protein methyltransferases.
| M.Wt | 348.871 | |
| Formula | C19H25ClN2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
2S-amino-N-[[4-(3,5-dimethylphenoxy)-3-methylphenyl]methyl]-propanamide, monohydrochloride |
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1. Ferreira de Freitas R, et al. J Med Chem. 2016 Jul 28;59(14):6838-47.
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