SHP1705 | Cryptochrome stabilizer | Probechem Biochemicals

Chemical Structure : SHP1705

SHP1705 (Cryptochrome modulator 50)

Catalog No.: PC-22367Not For Human Use, Lab Use Only.

SHP1705 is a small molecule cryptochrome (CRY) modulator and stabilizer, represses the expression of DBP, CRY1, and PER1, reduces glucose intolerance in obese, insulin-resistant mice.

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Biological Activity

SHP1705 is a small molecule cryptochrome (CRY) modulator and stabilizer, represses the expression of DBP, CRY1, and PER1, reduces glucose intolerance in obese, insulin-resistant mice.

Physicochemical Properties

M.Wt	345.35
Formula	C18H17F2N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(3-(3,6-difluoro-9H-carbazol-9-yl)-2-hydroxypropyl)imidazolidin-2-one

References

1. Paul S Humphries, et al. Bioorg Med Chem Lett. 2018 Feb 1;28(3):293-297.

2. Yuanzhong Pan, et al. bioRxiv [Preprint]. 2024 Apr 29:2024.04.26.590360.

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SHP1705 (Cryptochrome modulator 50)

Biological Activity

Physicochemical Properties

References

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