SIRT5 inhibitor 56

Chemical Structure : SIRT5 inhibitor 56

Catalog No.: PC-26868Not For Human Use, Lab Use Only.

SIRT5 inhibitor 56 is a potent, dual-pocket competitive Sirtuin 5 (SIRT5) inhibitor with IC50 of 0.29 uM.

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Biological Activity

SIRT5 inhibitor 56 is a potent, dual-pocket competitive Sirtuin 5 (SIRT5) inhibitor with IC50 of 0.29 uM.

M.Wt	610.65
Formula	C27H30N8O7S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-((1-((3-((5-((3-acetamidophenyl)carbamoyl)-2-(5-acetylthiophen-2-yl)pyrimidin-4-yl)amino)propyl)amino)-2-nitrovinyl)amino)propanoic acid

1. Jiang Y, et al. J Med Chem. 2026 May 17. doi: 10.1021/acs.jmedchem.5c03440.