Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : SIRT6 activator CL5D
Catalog No.: PC-38580Not For Human Use, Lab Use Only.
SIRT6 activator CL5D is a novel small-molecule activator of SIRT6 deacetylation, stimulates 4-fold activation of SIRT6 (1 uM) against H3K9ac (20 uM) at 3 uM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
SIRT6 activator CL5D is a novel small-molecule activator of SIRT6 deacetylation, stimulates 4-fold activation of SIRT6 (1 uM) against H3K9ac (20 uM) at 3 uM.
CL5D demonstrate competitive inhibition with Ki of 13.4 uM.
CL5D exhibited time-dependent deacetylation at H3K9 by SIRT6 in HEK293T cells.
| M.Wt | 731.565 | |
| Formula | C29H11Cl7N2O6 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Mark A Klein, et al. J Biol Chem. 2020 Jan 31;295(5):1385-1399.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
