SJ-172550 |CAS:431979-47-4 Probechem Biochemicals

Chemical Structure : SJ-172550

CAS No.: 431979-47-4

SJ-172550 (SJ172550;SJ 172550)

Catalog No.: PC-45010Not For Human Use, Lab Use Only.

SJ-172550 (SJ172550) is the first small molecule MDMX inhibitor that reversibly binds the p53-binding pocket of MDMX, disrupts MDMX-p53 interaction with EC50 of 2.3 uM.

Packing	Price	Stock
10 mg	$118	In stock
25 mg	$198	In stock
50 mg	$348	In stock
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Biological Activity

SJ-172550 (SJ172550) is the first small molecule MDMX inhibitor that reversibly binds the p53-binding pocket of MDMX, disrupts MDMX-p53 interaction with EC50 of 2.3 uM.

Physicochemical Properties

M.Wt	428.8655
Formula	C22H21ClN2O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Acetic acid, 2-[2-chloro-4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)methyl]-6-ethoxyphenoxy]-, methyl ester

References

1. Reed D, et al. J Biol Chem. 2010 Apr 2;285(14):10786-96.

2. Bista M, et al. PLoS One. 2012;7(6):e37518.

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SJ-172550 (SJ172550;SJ 172550)

Biological Activity

Physicochemical Properties

References

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