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SKF-38393 hydrobromide

Chemical Structure : SKF-38393 hydrobromide

CAS No.: 67287-49-4

SKF-38393 hydrobromide (SKF38393)

Catalog No.: PC-63114Not For Human Use, Lab Use Only.

SKF-38393 is a potent, selective D1/D5 receptor partial agonist with Ki of 1 and 0.5 nM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SKF-38393 is a potent, selective D1/D5 receptor partial agonist with Ki of 1 and 0.5 nM, respectively; shows little or no affinity for D2, D3, D3; exhibits stimulant and anorectic effects in rat models.

Physicochemical Properties

M.Wt 255.317
Formula C16H17NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol

References

1. Sibley DR, et al. Life Sci. 1982 Aug 16;31(7):637-45.

2. Geter-Douglass B, et al. J Pharmacol Exp Ther. 1997 Oct;283(1):7-15.

3. Habuchi Y, et al. Br J Pharmacol. 1997 Dec;122(8):1669-78.

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