Chemical Structure : SKF 38393 hydrochloride
CAS No.: 62717-42-4
Catalog No.: PC-43088Not For Human Use, Lab Use Only.
SKF 38393 is a potent, selective prototypical D1-like dopamine receptor with Ki of 1 and 0.5 nM for D1 and D5 receptors, shows little to no affinity for D2, D3 and D4 receptors.
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SKF 38393 hydrochloride is a potent, selective prototypical D1-like dopamine receptor with Ki of 1 and 0.5 nM for D1 and D5 receptors, shows little to no affinity for D2, D3 and D4 receptors.
SKF 38393 enhances the frequency of mEPSCs, and exhibits stimulant and anorectic effects, stimulates the release of glutamate in the hippocampus.
M.Wt | 291.7726 | |
Formula | C16H18ClNO2 | |
Appearance | Solid | |
Storage |
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Solubility |
DMSO: ≥ 34 mg/mL |
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Chemical Name/SMILES |
1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-, hydrochloride (1:1) |
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3. Sibley DR, et al. Life Sci. 1982 Aug 16;31(7):637-45.
4. Bouron A, et al. Neuroscience. 1999;94(4):1063-70.
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