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SKF 38393 hydrochloride

Chemical Structure : SKF 38393 hydrochloride

CAS No.: 62717-42-4

SKF 38393 hydrochloride ((±)-SKF-38393 hydrochloride;SKF-38393A)

Catalog No.: PC-43088Not For Human Use, Lab Use Only.

SKF 38393 is a potent, selective prototypical D1-like dopamine receptor with Ki of 1 and 0.5 nM for D1 and D5 receptors, shows little to no affinity for D2, D3 and D4 receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SKF 38393 is a potent, selective prototypical D1-like dopamine receptor with Ki of 1 and 0.5 nM for D1 and D5 receptors, shows little to no affinity for D2, D3 and D4 receptors; enhances the frequency of mEPSCs, and exhibits stimulant and anorectic effects, stimulates the release of glutamate in the hippocampus.

Physicochemical Properties

M.Wt 291.7726
Formula C16H18ClNO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 34 mg/mL

Chemical Name/SMILES

1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-, hydrochloride (1:1)

References

1. Geter-Douglass B, et al. J Pharmacol Exp Ther. 1997 Oct;283(1):7-15.

2. Habuchi Y, et al. Br J Pharmacol. 1997 Dec;122(8):1669-78.

3. Sibley DR, et al. Life Sci. 1982 Aug 16;31(7):637-45.

4. Bouron A, et al. Neuroscience. 1999;94(4):1063-70.

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