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SLK/STK10-IN-1

Chemical Structure : SLK/STK10-IN-1

CAS No.: 264210-49-3

SLK/STK10-IN-1

Catalog No.: PC-27757Not For Human Use, Lab Use Only.

SLK/STK10-IN-1 is a potent, selective dual inhibitor of SLK (STE20-like kinase) and STK10 (serine/threonine kinase 10) with IC50 of 1 uM for both in NanoBRET assays in HEK293 cells, shows good kinome-wide selectivity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SLK/STK10-IN-1 is a potent, selective dual inhibitor of SLK (STE20-like kinase) and STK10 (serine/threonine kinase 10) with IC50 of 1 uM for both in NanoBRET assays in HEK293 cells, shows good kinome-wide selectivity.

Physicochemical Properties

M.Wt 328.75
Formula C17H13ClN2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-((3-chlorophenyl)amino)-4-(2-methoxyphenyl)-1H-pyrrole-2,5-dione

References

1. Serafim RAM, et al. J Med Chem. 2021 Sep 23;64(18):13259-13278.

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