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SLU-PP-915

Chemical Structure : SLU-PP-915

CAS No.: 2285432-92-8

SLU-PP-915 (ERR agonist)

Catalog No.: PC-20982Not For Human Use, Lab Use Only.

SLU-PP-915 is a potent pan-ERR (Estrogen-related receptor) nuclear receptor agonist with EC50 of 414/435/378 nM for ERRα/ERRβ/ERRγ, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SLU-PP-915 is a potent pan-ERR (Estrogen-related receptor) nuclear receptor agonist with EC50 of 414/435/378 nM for ERRα/ERRβ/ERRγ, respectively.
SLU-PP-915 (5 uM) increased levels of gene expression (PGC1α, PDK4 and LDHA) in C2C12 myoblast cells.
SLU-PP-915 (20 mg/kg, i.p) ) induced expression of ERR target genes in muscles.

Physicochemical Properties

M.Wt 341.16
Formula C17H13BFNO3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3-(5-((2-fluorophenyl)carbamoyl)thiophen-2-yl)phenyl)boronic acid

References

1. Hampton CS, et al. Eur J Med Chem. 2023 Jun 25;258:115582.

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