SM-324405 |CAS:677773-91-0 Probechem Biochemicals

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Chemical Structure : SM-324405

CAS No.: 677773-91-0

SM-324405 (SM324405, SM 324405)

Catalog No.: PC-63387Not For Human Use, Lab Use Only.

SM-324405 is a potent, selective TLR7 agonist with EC50 of 50 nM, induces IFN-α and -γ expression in human PBMCs and mouse splenocytes, inhibits IL-5 production in human PBMCs in vitro.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$198	In stock
25 mg	$328	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SM-324405 is a potent, selective TLR7 agonist with EC50 of 50 nM, induces IFN-α and -γ expression in human PBMCs and mouse splenocytes, inhibits IL-5 production in human PBMCs in vitro.

Physicochemical Properties

M.Wt	385.424
Formula	C19H23N5O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Methyl 3-[(6-amino-2-butoxy-7,8-dihydro-8-oxo-9H-purin-9-yl)methyl]benzeneacetate

References

1. Kurimoto A, et al. J Med Chem. 2010 Apr 8;53(7):2964-72.

2. Biffen M, et al. Br J Pharmacol. 2012 May;166(2):573-86.

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SM-324405 (SM324405, SM 324405)

Biological Activity

Physicochemical Properties

References

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