Chemical Structure : SMN-C3
CAS No.: 1449597-34-5
Catalog No.: PC-62675Not For Human Use, Lab Use Only.
SMN-C3 is a selective, orally available small molecule SMN2 splicing modifier toward the production of full-length SMN2 messenger RNA with high selectivity.
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|---|---|---|---|
| 5 mg | $388 | In stock | |
| 10 mg | $598 | In stock | |
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SMN-C3 is a selective, orally available small molecule SMN2 splicing modifier toward the production of full-length SMN2 messenger RNA with high selectivity.
SMN-C3 increases SMN protein levels, improves motor function, and protects of the neuromuscular circuit in Δ7 mice.
SMN-C3 also extends the life span of the mice.
| M.Wt | 416.529 | |
| Formula | C24H28N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4H-Pyrido[1,2-a]pyrimidin-4-one, 2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-(1-ethyl-4-piperidinyl)-9-methyl- |
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1. Naryshkin NA, et al. Science. 2014 Aug 8;345(6197):688-93.

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