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Chemical Structure : SMU127
Catalog No.: PC-35705Not For Human Use, Lab Use Only.
SMU127 (SMU-127, ZINC666243) is a specific TLR1-TLR2 small molecule agonist with EC50 of 0.55 uM.
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SMU127 (SMU-127, ZINC666243) is a specific TLR1-TLR2 small molecule agonist with EC50 of 0.55 uM.
SMU127 stimulates NF-κB activation and promotes TNFα secretion in human macrophages and mononuclear cells, inhibits the growth of breast cancer tumors in BABL/c mice.
| M.Wt | 337.438 | |
| Formula | C16H23N3O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Chen Z, et al. Chem Commun (Camb). 2018 Oct 9;54(81):11411-11414.
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