SMYD3 inhibitor 49

Chemical Structure : SMYD3 inhibitor 49

Catalog No.: PC-49814Not For Human Use, Lab Use Only.

SMYD3 inhibitor 49 is a potent and selective SMYD3 inhibitor with IC50 of 6.3 and 44 nM in biochemical and cellular MEKK2me assays, respectively.

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Biological Activity

SMYD3 inhibitor 49 is a potent and selective SMYD3 inhibitor with IC50 of 6.3 and 44 nM in biochemical and cellular MEKK2me assays, respectively.

M.Wt	506.59
Formula	C22H33F3N4O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-cyclopropyl-N-(1-(((1r,4r)-4-((4,4,4-trifluorobutyl)amino)cyclohexyl)sulfonyl)piperidin-4-yl)isoxazole-3-carboxamide

1. Dai-Shi Su, et al. ACS Med Chem Lett. 2019 Dec 27;11(2):133-140.