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SOMCL-16-175

Chemical Structure : SOMCL-16-175

CAS No.: 1903682-64-3

SOMCL-16-175

Catalog No.: PC-20551Not For Human Use, Lab Use Only.

SOMCL-16-175 is a non-covalent, allosteric modulator targeting Hsp90α’s middle domain (Hsp90M) with binding Kd of 804 uM, inhibits breast cancer cell growth and proliferation.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

SOMCL-16-175 is a non-covalent, allosteric modulator targeting Hsp90α’s middle domain (Hsp90M) with binding Kd of 804 uM, inhibits breast cancer cell growth and proliferation.

Physicochemical Properties

M.Wt 242.10
Formula C10H9Cl2N3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

ClC1=C(CC2=CN=C(N)N2)C=CC(Cl)=C1

References

1. Zhou C, et al. iScience. 2020 Feb 21;23(2):100857.

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