SOS2 binder 1

Chemical Structure : SOS2 binder 1

Catalog No.: PC-23829Not For Human Use, Lab Use Only.

SOS2 binder 1 is a selective quinazoline-based compound that binds to the catalytic site of SOS2 with SPR KD of 4.6 uM, shows no binding to SOS1 up 200 uM.

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Biological Activity

SOS2 binder 1 is a selective quinazoline-based compound that binds to the catalytic site of SOS2 with SPR KD of 4.6 uM, shows no binding to SOS1 up 200 uM.

Physicochemical Properties

M.Wt	335.41
Formula	C19H21N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((4-(4-Methylpiperazin-1-yl)quinazolin-2-yl)amino)phenol

References

1. Zak KM, et al. J Med Chem. 2025 Jan 17. doi: 10.1021/acs.jmedchem.4c02007.

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SOS2 binder 1

Biological Activity

Physicochemical Properties

References

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