Chemical Structure : SPI-112
CAS No.: 1051387-90-6
Catalog No.: PC-23195Not For Human Use, Lab Use Only.
SPI-112 is a potent, selective and competitive SHP2 (PTPN11) inhibitor with IC50 of 1 uM.
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SPI-112 is a potent, selective and competitive SHP2 (PTPN11) inhibitor with IC50 of 1 uM.
M.Wt | 468.46 | |
Formula | C22H17FN4O5S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(Z)-3-(2-(5-(N-(4-Fluorobenzyl)sulfamoyl)-2-oxoindolin-3-ylidene)hydrazinyl)benzoic acid |
1. Chen L, et al. Biochem Pharmacol. 2010 Sep 15;80(6):801-10.
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