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SPI-112

Chemical Structure : SPI-112

CAS No.: 1051387-90-6

SPI-112 (SPI 112)

Catalog No.: PC-23195Not For Human Use, Lab Use Only.

SPI-112 is a potent, selective and competitive SHP2 (PTPN11) inhibitor with IC50 of 1 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SPI-112 is a potent, selective and competitive SHP2 (PTPN11) inhibitor with IC50 of 1 uM.

Physicochemical Properties

M.Wt 468.46
Formula C22H17FN4O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(Z)-3-(2-(5-(N-(4-Fluorobenzyl)sulfamoyl)-2-oxoindolin-3-ylidene)hydrazinyl)benzoic acid

References

1. Chen L, et al. Biochem Pharmacol. 2010 Sep 15;80(6):801-10.

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