SQ-22536 | Adenylyl Cyclase inhibitor | Probechem Biochemicals

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Chemical Structure : SQ-22536

CAS No.: 17318-31-9

SQ-22536 (SQ22536)

Catalog No.: PC-42132Not For Human Use, Lab Use Only.

SQ-22536 is a potent, non-competitive Adenylyl Cyclase inhibitor with IC50 of 1.4 uM.

Packing	Price	Stock
10 mg	$78	In stock
25 mg	$138	In stock
50 mg	$218	In stock
100 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SQ-22536 is a potent, non-competitive Adenylyl Cyclase inhibitor with IC50 of 1.4 uM.
SQ-22536 abolishes the iloprost-induced elevation in cyclic AMP while having no significant effect on relaxation in isolated guinea-pig aorta.

Physicochemical Properties

M.Wt	205.2165
Formula	C9H11N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	DMSO: ≥ 29 mg/mL
Chemical Name/SMILES	9H-Purin-6-amine, 9-(tetrahydro-2-furanyl)-

References

1. Fabbri E, et al. J Enzyme Inhib. 1991;5(2):87-98.

2. Hourani SM, et al. Br J Pharmacol. 2001 Jul;133(6):833-40.

3. Turcato S, et al. Br J Pharmacol. 1999 Feb;126(4):845-7.

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SQ-22536 (SQ22536)

Biological Activity

Physicochemical Properties

References

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