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SR-11237

Chemical Structure : SR-11237

CAS No.: 146670-40-8

SR-11237 (BMS-649;BMS649;SR11237)

Catalog No.: PC-70297Not For Human Use, Lab Use Only.

SR-11237 (BMS-649) is a selective pan retinoid X receptor (RXR) agonist with no retinoid A receptor (RAR) activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SR-11237 (BMS-649) is a selective pan retinoid X receptor (RXR) agonist with no retinoid A receptor (RAR) activity.

Physicochemical Properties

M.Wt 380.48
Formula C24H28O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-dioxolan-2-yl)benzoic acid

References

1. Bourguet W, et al. Mol Cell. 2000 Feb;5(2):289-98.

2. Benoit G, et al. EMBO J. 1999 Dec 15;18(24):7011-8.

3. Gendimenico GJ, et al. J Invest Dermatol. 1994 May;102(5):676-80.

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