SR-419 | α5-GABAA receptor inhibitor | Probechem Biochemicals

Chemical Structure : SR-419

SR-419 (SR419)

Catalog No.: PC-25268Not For Human Use, Lab Use Only.

SR-419 is a BBB-impermeable, selective α5-GABAA receptor (GABRA5) inhibitor, shows specific binding to the benzodiazepine site of the GABRA5 receptor, exhibits potent peripheral analgesic effects.

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Biological Activity

SR-419 is a BBB-impermeable, selective α5-GABAA receptor (GABRA5) inhibitor, shows specific binding to the benzodiazepine site of the GABRA5 receptor, exhibits potent peripheral analgesic effects.

Physicochemical Properties

M.Wt	473.49
Formula	C24H23N7O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-isopropyl-6-(((3-(5-(methoxymethyl)isoxazol-3-yl)-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)oxy)methyl)nicotinamide

References

1. Chen Y, et al. Br J Pharmacol. 2025 Aug 9. doi: 10.1111/bph.70150.

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SR-419 (SR419)

Biological Activity

Physicochemical Properties

References

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